Version 3, 18 August 2025
NIHR Bristol Evidence Synthesis Group
Contributors: Jennifer Palmer, Katie Webster, Gabriel Barreto, Francesca Spiga, Philippa Davies, Sarah Davies, Sarah Dawson, Deborah Caldwell, Julian Higgins
Background
Wearable devices are increasingly used by the general public and healthcare professionals with the aim of monitoring general health and facilitating earlier diagnosis. We aimed to assess the current availability of systematic review evidence on the use of wearable devices for early detection of primary disease (Use case 1), the promotion of behaviour changes to improve health (Use case 2), and pre- and post-operative care (Use case 3).
These were the aims set out in our original proposal:
Primary aim: to understand the synthesized evidence in relation to wearables according to each of three use cases:
- Use case 1 (UC1): Earlier detection of (primary and secondary) conditions, with a focus on clinical effectiveness.
- Use case 2 (UC2): Behaviour change for better health outcomes, and
- Use case 3 (UC3): Pre-operative assessment and post-operative recovery.
Secondary aim: to indicate where there are evidence gaps, to enable the targeting of evidence-gathering to inform development of wearables policy.
Methods
We searched Ovid Medline and Ovid Embase for articles published from 1 January 2020 to 21 May 2025. We independently screened titles and abstracts from 2372 records for inclusion in duplicate, with conflicts resolved by team discussion. 321 full texts were each assessed for eligibility by one team member, with all excluded articles at this stage checked by a second team member and discussed if needed. Following this process, we included 183 systematic reviews: 52 reviews for Use case 1; 110 reviews for Use case 2, and 23 reviews for Use case 3.
Where the intervention of interest within the systematic review was wearables entirely, we extracted their search information and results, eligibility criteria, and the bottom-line results/conclusions from the review. Where the intervention of interest was a wider intervention that included wearables within, we extracted more limited information on the intervention type that included wearables eligible for the review, and health condition, health behaviour or type of surgery for use cases 1, 2 or 3 respectively.
All included reviews were included on the visual Evidence Gap Maps, produced using EPPI reviewer and the Evidence Gap Map software, EPPI Mapper.
Results
Use-case 1: Wearables for earlier detection or diagnosis of primary conditions
We identified 25 systematic reviews that matched our eligibility criteria for wearables for Use case 1, and 27 systematic reviews on wider interventions that included wearables. We identified systematic reviews investigating both clinical effectiveness (whether the wearable(s) lead(s) to a primary diagnosis earlier than had the wearable not been worn) and clinical accuracy (how accurate the wearable(s) is/are at leading to a diagnosis, which could be sensitivity, specificity or another suitable measure).
We included nine reviews for secondary detection of CVD outcomes within CVD populations. These are included in the UC1 map (filter by population “with current or previous CVD/mixed”) to see only these reviews.
For each map, refer to the ‘About’ tab at the top of the screen for more information. The ‘Filter’ options can be used to filter results by number of included studies in the review, population, or study designs included. Once the desired filter is selected, click on ‘view records’ to see the relevant systematic reviews. The key for colour-coding is at the bottom of the map.
The evidence gap map ‘UC1 – by effectiveness_accuracy’ shows type of wearable/intervention that includes wearables as rows and primary health condition detecting as columns, colour-coded by whether the review was investigating clinical effectiveness (pink) or clinical accuracy (purple).
The evidence gap map ‘UC1 – by population’ shows type of wearable/intervention that includes wearables as rows and primary health condition detecting as columns, colour-coded by whether the review was investigating a general/healthy population (pink), people suspected of having the health condition (blue), a mixed with/without a health condition population (purple), or population information not extracted/not reported (green).
Use case 2 – general population: Wearables for behaviour change for better health outcomes
We identified 43 systematic reviews matched our eligibility criteria for wearables for Use case 2, and 67 systematic reviews on wider interventions that included wearables.
The evidence gap map ‘UC2_by_population’ shows type of wearable/intervention that includes wearables as rows and health behaviour detecting as columns, colour-coded by whether the review was investigating a general/healthy population (green), with a health condition (pink, to add), or mixed population with/without a health condition (purple).
As there are a lot of systematic reviews included for Use case 2, particularly investigating the use of wearables on improving physical activity levels in those with health conditions, there is an additional filter for populations included in Use case 2. This may be useful to see reviews in those with a particular health condition, such as cancer, cardiovascular disease or mental health. Please refer to the ‘About’ tab at the top of the screen for more information and the ‘Filter’ tab to see all the filter options.
Use case 3 – Wearables for pre-operative assessment and post-operative recovery
We identified 11 systematic reviews that matched our eligibility criteria for wearables for Use case 3, and 12 systematic reviews on wider interventions that included wearables. We identified systematic reviews investigating both pre-operative assessment and post operative recovery.
The evidence gap map ‘UC3_by_pre-post’ shows type of wearable/intervention that includes wearables as rows and operation type as columns, colour-coded by whether the review was investigating pre-operative monitoring (green) or post-operative assessment (pink) (note, many reviews looked at both): UC3_by_pre-post.html / UC3_by_pre-post.zip
The evidence gap map ‘UC3_by_population’ shows type of wearable/intervention that includes wearables as rows and operation type as columns, colour-coded by whether the review was investigating an adult population (pink), older adult population (purple), or population information not extracted (green): UC3_by_population.html / UC3_by_population.zip
References to included systematic reviews
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- Abd-Alrazaq A, Aslam H, AlSaad R, Alsahli M, Ahmed A, Damseh R, et al. Detection of Sleep Apnea Using Wearable AI: Systematic Review and Meta-Analysis. J Med Internet Res. 2024;26:e58187.
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- Belani S, Wahood W, Hardigan P, Placzek AN, Ely S. Accuracy of Detecting Atrial Fibrillation: A Systematic Review and Meta-Analysis of Wrist-Worn Wearable Technology. Cureus. 2021;13(12):e20362.
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- Lee MA, Song M, Bessette H, Roberts Davis M, Tyner TE, Reid A. Use of wearables for monitoring cardiometabolic health: A systematic review. International Journal of Medical Informatics. 2023;179:105218.
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- Mitratza M, Goodale BM, Shagadatova A, Kovacevic V, van de Wijgert J, Brakenhoff TB, et al. The performance of wearable sensors in the detection of SARS-CoV-2 infection: a systematic review. Lancet Digit Health. 2022;4(5):e370-e83.
- Moshawrab M, Adda M, Bouzouane A, Ibrahim H, Raad A. Smart Wearables for the Detection of Cardiovascular Diseases: A Systematic Literature Review. Sensors (Basel). 2023;23(2):11.
- Nazarian S, Lam K, Darzi A, Ashrafian H. Diagnostic Accuracy of Smartwatches for the Detection of Cardiac Arrhythmia: Systematic Review and Meta-analysis. J Med Internet Res. 2021;23(8):e28974.
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- Sanches CA, Silva GA, Librantz AFH, Sampaio LMM, Belan PA. Wearable Devices to Diagnose and Monitor the Progression of COVID-19 Through Heart Rate Variability Measurement: Systematic Review and Meta-Analysis. J Med Internet Res. 2023;25:e47112.
- Sastimoglu Z, Subramaniam S, Faisal AI, Jiang W, Ye A, Deen MJ. Wearable PPG Based BP Estimation Methods: A Systematic Review and Meta-Analysis. IEEE Journal of Biomedical & Health Informatics. 2025;29(4):2439-52.
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- Sibomana O, Hakayuwa CM, Obianke A, Gahire H, Munyantore J, Chilala MM. Diagnostic accuracy of ECG smart chest patches versus PPG smartwatches for atrial fibrillation detection: a systematic review and meta-analysis. BMC Cardiovascular Disorders. 2025;25(1):132.
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